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Evaluation of Mannose Binding Lectin Gene Variants in Pediatric Influenza Virus-Related Critical Illness

Background: Mannose-binding lectin (MBL) is an innate immune protein with strong biologic plausibility for protecting against influenza virus-related sepsis and bacterial co-infection. In an autopsy cohort of 105 influenza-infected young people, carriage of the deleterious MBL gene MBL2_Gly54Asp(“B”...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Levy, Emily R., Yip, Wai-Ki, Super, Michael, Ferdinands, Jill M., Mistry, Anushay J., Newhams, Margaret M., Zhang, Yu, Su, Helen C., McLaughlin, Gwenn E., Sapru, Anil, Loftis, Laura L., Weiss, Scott L., Hall, Mark W., Cvijanovich, Natalie, Schwarz, Adam, Tarquinio, Keiko M., Mourani, Peter M., Randolph, Adrienne G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6518443/
https://ncbi.nlm.nih.gov/pubmed/31139182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01005
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