Evaluation of Mannose Binding Lectin Gene Variants in Pediatric Influenza Virus-Related Critical Illness

Background: Mannose-binding lectin (MBL) is an innate immune protein with strong biologic plausibility for protecting against influenza virus-related sepsis and bacterial co-infection. In an autopsy cohort of 105 influenza-infected young people, carriage of the deleterious MBL gene MBL2_Gly54Asp(“B”...

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Publicado en:Front Immunol
Autores principales: Levy, Emily R., Yip, Wai-Ki, Super, Michael, Ferdinands, Jill M., Mistry, Anushay J., Newhams, Margaret M., Zhang, Yu, Su, Helen C., McLaughlin, Gwenn E., Sapru, Anil, Loftis, Laura L., Weiss, Scott L., Hall, Mark W., Cvijanovich, Natalie, Schwarz, Adam, Tarquinio, Keiko M., Mourani, Peter M., Randolph, Adrienne G.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6518443/
https://ncbi.nlm.nih.gov/pubmed/31139182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01005
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