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The dual structural roles of the membrane distal region of the α-integrin cytoplasmic tail during integrin inside-out activation

Studies on the mechanism of integrin inside-out activation have been focused on the role of β-integrin cytoplasmic tails, which are relatively conserved and bear binding sites for the intracellular activators including talin and kindlin. Cytoplasmic tails for α-integrins share a conserved GFFKR moti...

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Détails bibliographiques
Publié dans:J Cell Sci
Auteurs principaux: Liu, Jiafu, Wang, Zhengli, Myat, Aye, Ma, Yan-Qing, Zhu, Jieqing
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6518327/
https://ncbi.nlm.nih.gov/pubmed/25749862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.160663
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