Error-prone meiotic division and subfertility in mice with oocyte-conditional knockdown of pericentrin

Mouse oocytes lack canonical centrosomes and instead contain unique acentriolar microtubule-organizing centers (aMTOCs). To test the function of these distinct aMTOCs in meiotic spindle formation, pericentrin (Pcnt), an essential centrosome/MTOC protein, was knocked down exclusively in oocytes by us...

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Bibliografiske detaljer
Udgivet i:J Cell Sci
Main Authors: Baumann, Claudia, Wang, Xiaotian, Yang, Luhan, Viveiros, Maria M.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6518315/
https://ncbi.nlm.nih.gov/pubmed/28193732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.196188
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