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Depletion of Pericentrin in Mouse Oocytes Disrupts Microtubule Organizing Center Function and Meiotic Spindle Organization

Accurate chromosome segregation is dependent on the formation and stability of the microtubule spindle apparatus. Meiotic spindle assembly in oocytes differs from the process used during mitosis, and is regulated by unique microtubule organizing centers (MTOCs) that lack centrioles. To gain insight...

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Détails bibliographiques
Publié dans:Mol Reprod Dev
Auteurs principaux: Ma, Wei, Viveiros, Maria M.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229429/
https://ncbi.nlm.nih.gov/pubmed/25266793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrd.22422
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