TET1 contributes to allergic airway inflammation and regulates interferon and aryl hydrocarbon receptor signaling pathways in bronchial epithelial cells

Previous studies have suggested a role for Tet1 in the pathogenesis of childhood asthma. However, how Tet1 contributes to asthma remains unknown. Here we used mice deficient for Tet1 in a well-established model of allergic airway inflammation and demonstrated that loss of Tet1 increased disease seve...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Burleson, J. D., Siniard, Dylan, Yadagiri, Veda K., Chen, Xiaoting, Weirauch, Matthew T., Ruff, Brandy P., Brandt, Eric B., Hershey, Gurjit K. Khurana, Ji, Hong
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6517446/
https://ncbi.nlm.nih.gov/pubmed/31089182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43767-6
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