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The dynamics of adaptive genetic diversity during the early stages of clonal evolution
The dynamics of genetic diversity in large clonally evolving cell populations are poorly understood, despite having implications for the treatment of cancer and microbial infections. Here, we combine barcode lineage tracking, sequencing of adaptive clones and mathematical modelling of mutational dyn...
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| Yayımlandı: | Nat Ecol Evol |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6517070/ https://ncbi.nlm.nih.gov/pubmed/30598529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41559-018-0758-1 |
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