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The dynamics of adaptive genetic diversity during the early stages of clonal evolution
The dynamics of genetic diversity in large clonally evolving cell populations are poorly understood, despite having implications for the treatment of cancer and microbial infections. Here, we combine barcode lineage tracking, sequencing of adaptive clones and mathematical modelling of mutational dyn...
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| 出版年: | Nat Ecol Evol |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6517070/ https://ncbi.nlm.nih.gov/pubmed/30598529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41559-018-0758-1 |
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