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Morphogen gradient reconstitution reveals Hedgehog pathway design principles
In developing tissues, cells estimate their spatial position by sensing graded concentrations of diffusible signaling proteins called morphogens. Morphogen-sensing pathways exhibit diverse molecular architectures, whose roles in controlling patterning dynamics and precision remain unclear. Here, com...
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| Udgivet i: | Science |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6516753/ https://ncbi.nlm.nih.gov/pubmed/29622726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aao0645 |
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