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Translational control through differential ribosome pausing during amino acid limitation in mammalian cells
Limitation for amino acids is thought to regulate translation in mammalian cells primarily by signaling through the kinases mTORC1 and GCN2. We find that a selective loss of arginine tRNA charging during limitation for the amino acid arginine regulates translation through ribosome pausing at two of...
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| Publié dans: | Mol Cell |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6516488/ https://ncbi.nlm.nih.gov/pubmed/30029003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.06.041 |
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