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An Integrated Approach Reveals Regulatory Controls on Bacterial Translation Elongation

Ribosomes elongate at a non-uniform rate during translation. Theoretical models and experiments disagree on the in vivo determinants of elongation rate and the mechanism by which elongation rate affects protein levels. To resolve this conflict, we measured transcriptome-wide ribosome occupancy under...

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Библиографические подробности
Опубликовано в: :Cell
Главные авторы: Subramaniam, Arvind R., Zid, Brian M., O’Shea, Erin K.
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243059/
https://ncbi.nlm.nih.gov/pubmed/25416955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.10.043
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