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An Integrated Approach Reveals Regulatory Controls on Bacterial Translation Elongation

Ribosomes elongate at a non-uniform rate during translation. Theoretical models and experiments disagree on the in vivo determinants of elongation rate and the mechanism by which elongation rate affects protein levels. To resolve this conflict, we measured transcriptome-wide ribosome occupancy under...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Subramaniam, Arvind R., Zid, Brian M., O’Shea, Erin K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243059/
https://ncbi.nlm.nih.gov/pubmed/25416955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.10.043
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