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Optimal inference for Simon’s two-stage design with over or under enrollment at the second stage
Simon’s two-stage designs are widely used in clinical trials to assess the activity of a new treatment. In practice, it is often the case that the second stage sample size is different from the planned one. For this reason, the critical value for the second stage is no longer valid for statistical i...
Shranjeno v:
| izdano v: | Commun Stat Simul Comput |
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| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6516485/ https://ncbi.nlm.nih.gov/pubmed/31097866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/03610918.2017.1307398 |
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