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Construction and characterisation of a heparan sulphate heptasaccharide microarray

A targeted heptasaccharide library was synthesised to prepare a heparan sulphate (HS) microarray. The array was probed with two glycan-binding proteins, HS 3-O-sulphotransferase 1 and antithrombin, demonstrating the binding selectivity between HS and proteins. The HS microarray technique will accele...

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Dades bibliogràfiques
Publicat a:Chem Commun (Camb)
Autors principals: Yang, Jianhong, Hsieh, Po-Hung, Liu, Xinyue, Zhou, Wen, Zhang, Xing, Zhao, Jing, Xu, Yongmei, Zhang, Fuming, Linhardt, Robert J., Liu, Jian
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6516466/
https://ncbi.nlm.nih.gov/pubmed/28106177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6cc08204a
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