Endothelial toll‐like receptor 4 maintains lung integrity via epigenetic suppression of p16(INK4a)

We previously reported that the canonical innate immune receptor toll‐like receptor 4 (TLR4) is critical in maintaining lung integrity. However, the molecular mechanisms via which TLR4 mediates its effect remained unclear. In the present study, we identified distinct contributions of lung endothelia...

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Bibliografiska uppgifter
I publikationen:Aging Cell
Huvudupphovsmän: Kim, So‐Jin, Shan, Peiying, Hwangbo, Cheol, Zhang, Yi, Min, Jin‐Na, Zhang, Xuchen, Ardito, Taylor, Li, Alfred, Peng, Tien, Sauler, Maor, Lee, Patty J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2019
Ämnen:
Original Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6516428/
https://ncbi.nlm.nih.gov/pubmed/30790400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12914
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