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Association of Epigenetic Age and p16(INK4a) With Markers of T-Cell Composition in a Healthy Cohort

How the measurement of aging biomarkers in peripheral blood T-lymphocytes (PBTLs) is influenced by cell composition is unclear. Here, we collected peripheral blood and isolated CD3(+) PBTLs from 117 healthy couples between the ages of 21 and 72. Each sample was profiled for Horvath epigenetic clock...

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Détails bibliographiques
Publié dans:J Gerontol A Biol Sci Med Sci
Auteurs principaux: Burd, Christin E, Peng, Juan, Laskowski, Bryon F, Hollyfield, Jennifer L, Zhang, Suohui, Fadda, Paolo, Yu, Lianbo, Andridge, Rebecca R, Kiecolt-Glaser, Janice K
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7662168/
https://ncbi.nlm.nih.gov/pubmed/32361724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glaa108
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