Pharmacological clearance of senescent cells improves survival and recovery in aged mice following acute myocardial infarction

Cardiovascular disease is the leading cause of death in individuals over 60 years old. Aging is associated with an increased prevalence of coronary artery disease and a poorer prognosis following acute myocardial infarction (MI). With age, senescent cells accumulate in tissues, including the heart,...

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Publicat a:Aging Cell
Autors principals: Walaszczyk, Anna, Dookun, Emily, Redgrave, Rachael, Tual‐Chalot, Simon, Victorelli, Stella, Spyridopoulos, Ioakim, Owens, Andrew, Arthur, Helen M., Passos, João F., Richardson, Gavin D.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Short Take
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6516151/
https://ncbi.nlm.nih.gov/pubmed/30920115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12945
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