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Selective breeding as a tool to probe skeletal response to high voluntary locomotor activity in mice

We present a novel mouse-model for the study of skeletal structure and evolution, based on selective breeding for high levels of voluntary wheel running. Whereas traditional models (originally inbred strains, more recently knockouts and transgenics) rely on the study of mutant or laboratory-manipula...

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Detalhes bibliográficos
Publicado no:Integr Comp Biol
Main Authors: Middleton, Kevin M., Kelly, Scott A., Garland, Theodore
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6515713/
https://ncbi.nlm.nih.gov/pubmed/21669801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/icb/icn057
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