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Selective breeding as a tool to probe skeletal response to high voluntary locomotor activity in mice

We present a novel mouse-model for the study of skeletal structure and evolution, based on selective breeding for high levels of voluntary wheel running. Whereas traditional models (originally inbred strains, more recently knockouts and transgenics) rely on the study of mutant or laboratory-manipula...

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Pubblicato in:Integr Comp Biol
Autori principali: Middleton, Kevin M., Kelly, Scott A., Garland, Theodore
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6515713/
https://ncbi.nlm.nih.gov/pubmed/21669801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/icb/icn057
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