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Targeting Tyro3, Axl and MerTK (TAM receptors): implications for macrophages in the tumor microenvironment

Tumor-associated macrophages are an abundant cell type in the tumor microenvironment. These macrophages serve as a promising target for treatment of cancer due to their roles in promoting cancer progression and simultaneous immunosuppression. The TAM receptors (Tyro3, Axl and MerTK) are promising th...

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Bibliografiske detaljer
Udgivet i:Mol Cancer
Main Authors: Myers, Kayla V., Amend, Sarah R., Pienta, Kenneth J.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6515593/
https://ncbi.nlm.nih.gov/pubmed/31088471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-019-1022-2
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