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Establishment and Characterization of 5-Fluorouracil-Resistant Human Colorectal Cancer Stem-Like Cells: Tumor Dynamics under Selection Pressure

5-Fluorouracil (5-FU) remains the gold standard of first-line treatment for colorectal cancer (CRC). Although it may initially debulk the tumor mass, relapses frequently occur, indicating the existence of cancer cells that are therapy-resistant and are capable of refueling tumor growth. To identify...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Francipane, Maria Giovanna, Bulanin, Denis, Lagasse, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6515384/
https://ncbi.nlm.nih.gov/pubmed/31013771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20081817
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