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Interleukin-4 and Interleukin-13 Exacerbate Neurotoxicity of Prothrombin Kringle-2 in Cortex In Vivo via Oxidative Stress

The present study investigated the effects of activated microglia-derived interleukin-4 (IL-4) and IL-13 on neurodegeneration in prothrombin kringle-2 (pKr-2)-treated rat cortex. pKr-2 was unilaterally injected into the Sprague–Dawley rat cerebral cortex and IL-4 and IL-13 neutralizing antibody was...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Jeong, Jae Yeong, Chung, Young Cheul, Jin, Byung Kwan
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6515094/
https://ncbi.nlm.nih.gov/pubmed/31010119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20081927
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