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Inhibitory Effect of Berberine on Broiler P-glycoprotein Expression and Function: In Situ and In Vitro Studies

Overcoming P-glycoprotein (P-gp) efflux is a strategy to improve the absorption and pharmacokinetics of its substrate drugs. Berberine inhibits P-gp and thereby increases the bioavailability of the P-gp substrate digoxin in rodents. However, the effects of berberine on P-gp in chickens are still unc...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Zhang, Yujuan, Guo, Li, Huang, Jinhu, Sun, Yong, He, Fang, Zloh, Mire, Wang, Liping
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6515058/
https://ncbi.nlm.nih.gov/pubmed/31013627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20081966
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