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Age-Related P-Glycoprotein Expression in the Intestine and Affecting the Pharmacokinetics of Orally Administered Enrofloxacin in Broilers

Bioavailability is the most important factor for the efficacy of any drug and it is determined by P- glycoprotein (P-gp) expression. Confirmation of P-gp expression during ontogeny is needed for understanding the differences in therapeutic efficacy of any drug in juvenile and adult animals. In this...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Guo, Mengjie, Bughio, Shamsuddin, Sun, Yong, Zhang, Yu, Dong, Lingling, Dai, Xiaohua, Wang, Liping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774662/
https://ncbi.nlm.nih.gov/pubmed/24066110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074150
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