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DNA Methylation Contributes to the Differential Expression Levels of Mecp2 in Male Mice Neurons and Astrocytes

Methyl CpG binding protein-2 (MeCP2) isoforms (E1 and E2) are important epigenetic regulators in brain cells. Accordingly, MeCP2 loss- or gain-of-function mutation causes neurodevelopmental disorders, including Rett syndrome (RTT), MECP2 duplication syndrome (MDS), and autism spectrum disorders (ASD...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Liyanage, Vichithra R.B., Olson, Carl O., Zachariah, Robby M., Davie, James R., Rastegar, Mojgan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514911/
https://ncbi.nlm.nih.gov/pubmed/31013990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20081845
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