Anti-Apoptotic Effects of Recombinant Human Hepatocyte Growth Factor on Hepatocytes Were Associated with Intrahepatic Hemorrhage Suppression Indicated by the Preservation of Prothrombin Time

Hepatocyte growth factor (HGF) is an endogenously expressed bioactive substance that has a strong anti-apoptotic effect. In this study, we biochemically and histologically characterized the effects of rh-HGF on in vitro human hepatocyte injury and mouse acute liver failure (ALF) models, both of whic...

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Publicat a:Int J Mol Sci
Autors principals: Motoi, Sotaro, Toyoda, Hiroko, Obara, Takashi, Ohta, Etsuko, Arita, Yoshihisa, Negishi, Kana, Moriya, Katsuhiro, Kuboi, Yoshikazu, Soejima, Motohiro, Imai, Toshio, Ido, Akio, Tsubouchi, Hirohito, Kawano, Tetsu
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514566/
https://ncbi.nlm.nih.gov/pubmed/31013780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20081821
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