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Tumour necrosis factor α augments the inhibitory effects of CTLA‐4‐Ig on osteoclast generation from human monocytes via induction of CD80 expression
Cytotoxic T lymphocyte antigen‐4‐immunoglobulin (CTLA‐4‐Ig) exerts anti‐rheumatic action via negative regulation of the co‐stimulation process between antigen‐presenting cells and T cells. CTLA‐4‐Ig also binds to CD80/CD86 on monocytes of osteoclast precursors. However, little is known about the eff...
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| Publicado no: | Clin Exp Immunol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6514374/ https://ncbi.nlm.nih.gov/pubmed/30724348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13271 |
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