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Effects of CTLA4-Ig on human monocytes
BACKGROUND: Abatacept, a CTLA4-Ig fusion protein attenuates T cell activation by inhibiting the CD80/86-CD28 costimulatory pathway that is required for the proper T cell activation and thus displays beneficial effects in the treatment of rheumatoid arthritis (RA). Although some studies have disclose...
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| Publicado no: | Inflamm Regen |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5725919/ https://ncbi.nlm.nih.gov/pubmed/29259723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41232-017-0054-5 |
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