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Protein inhibitor of activated STAT1 Ser(503) phosphorylation‐mediated Elk‐1 SUMOylation promotes neuronal survival in APP/PS1 mice
BACKGROUND AND PURPOSE: Protein inhibitor of activated STAT1 (PIAS1) is phosphorylated by IKKα at Ser(90) in a PIAS1 E3 ligase activity‐dependent manner. Whether PIAS1 is also phosphorylated at other residues and the functional significance of these additional phosphorylation events are not known. T...
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| Udgivet i: | Br J Pharmacol |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6514297/ https://ncbi.nlm.nih.gov/pubmed/30849179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14656 |
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