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Protein inhibitor of activated STAT1 Ser(503) phosphorylation‐mediated Elk‐1 SUMOylation promotes neuronal survival in APP/PS1 mice

BACKGROUND AND PURPOSE: Protein inhibitor of activated STAT1 (PIAS1) is phosphorylated by IKKα at Ser(90) in a PIAS1 E3 ligase activity‐dependent manner. Whether PIAS1 is also phosphorylated at other residues and the functional significance of these additional phosphorylation events are not known. T...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Br J Pharmacol
Egile Nagusiak: Liu, Shau‐Yu, Ma, Yun‐Li, Hsu, Wei‐Lun, Chiou, Hsin‐Ying, Lee, Eminy H.Y.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514297/
https://ncbi.nlm.nih.gov/pubmed/30849179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14656
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