Small‐molecule inhibition of prostaglandin E receptor 2 impairs cyclooxygenase‐associated malignant glioma growth

BACKGROUND AND PURPOSE: An up‐regulation of COX‐2 in malignant gliomas causes excessive synthesis of PGE(2), which is thought to facilitate brain tumour growth and invasion. However, which downstream PGE(2) receptor subtype (i.e., EP(1)–EP(4)) directly contributes to COX activity‐promoted glioma gro...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Br J Pharmacol
Egile Nagusiak: Qiu, Jiange, Li, Qianqian, Bell, Katherine A., Yao, Xue, Du, Yifeng, Zhang, Erik, Yu, Jane J., Yu, Ying, Shi, Zhi, Jiang, Jianxiong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2019
Gaiak:
Research Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514294/
https://ncbi.nlm.nih.gov/pubmed/30761522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14622
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