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Small‐molecule inhibition of prostaglandin E receptor 2 impairs cyclooxygenase‐associated malignant glioma growth
BACKGROUND AND PURPOSE: An up‐regulation of COX‐2 in malignant gliomas causes excessive synthesis of PGE(2), which is thought to facilitate brain tumour growth and invasion. However, which downstream PGE(2) receptor subtype (i.e., EP(1)–EP(4)) directly contributes to COX activity‐promoted glioma gro...
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| Publicado no: | Br J Pharmacol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6514294/ https://ncbi.nlm.nih.gov/pubmed/30761522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14622 |
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