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Implications of genetic variation of common Drug Metabolizing Enzymes and ABC Transporters among the Pakistani Population

Genetic polymorphism of drug metabolizing enzymes and transporters may influence drug response. The frequency varies substantially between ethnicities thus having implications on appropriate selection and dosage of various drugs in different populations. The distribution of genetic polymorphisms in...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Afsar, Nasir Ali, Bruckmueller, Henrike, Werk, Anneke Nina, Nisar, Muhammad Kashif, Ahmad, H. R., Cascorbi, Ingolf
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514210/
https://ncbi.nlm.nih.gov/pubmed/31086207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43736-z
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