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Implications of genetic variation of common Drug Metabolizing Enzymes and ABC Transporters among the Pakistani Population

Genetic polymorphism of drug metabolizing enzymes and transporters may influence drug response. The frequency varies substantially between ethnicities thus having implications on appropriate selection and dosage of various drugs in different populations. The distribution of genetic polymorphisms in...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Afsar, Nasir Ali, Bruckmueller, Henrike, Werk, Anneke Nina, Nisar, Muhammad Kashif, Ahmad, H. R., Cascorbi, Ingolf
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514210/
https://ncbi.nlm.nih.gov/pubmed/31086207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43736-z
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