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Soluble adenylyl cyclase links Ca(2+) entry to Ca(2+)/cAMP-response element binding protein (CREB) activation in vascular smooth muscle

Ca(2+)-transcription coupling controls gene expression patterns that define vascular smooth muscle cell (VSMC) phenotype. Although not well understood this allows normally contractile VSMCs to become proliferative following vessel injury, a process essential for repair but which also contributes to...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Parker, Tony, Wang, Kai-Wen, Manning, Declan, Dart, Caroline
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514005/
https://ncbi.nlm.nih.gov/pubmed/31086231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43821-3
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