Synthesis and evaluation of (64)Cu-radiolabeled NOTA-cetuximab ((64)Cu-NOTA-C225) for immuno-PET imaging of EGFR expression

OBJECTIVE: Epidermal growth factor receptor (EGFR) is overexpressed in a wide variety of solid tumors, serving as a well-characterized target for cancer imaging or therapy. In this study, we aimed to design and synthesize a radiotracer, (64)Cu-NOTA-C225, targeting EGFR for tumor positron emission to...

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Detalhes bibliográficos
Publicado no:Chin J Cancer Res
Main Authors: Xu, Xiaoxia, Liu, Teli, Liu, Fei, Guo, Xiaoyi, Xia, Lei, Xie, Qing, Li, Nan, Huang, Haifeng, Yang, Xianteng, Xin, Yangchun, Zhu, Hua, Yang, Zhi
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6513748/
https://ncbi.nlm.nih.gov/pubmed/31156310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21147/j.issn.1000-9604.2019.02.14
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