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Emerging Evidence of Chromosome Folding by Loop Extrusion

Chromosome organization poses a remarkable physical problem with many biological consequences: How can molecular interactions between proteins at the nanometer scale organize micron-long chromatinized DNA molecules, insulating or facilitating interactions between specific genomic elements? The mecha...

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Bibliographic Details
Published in:Cold Spring Harb Symp Quant Biol
Main Authors: Fudenberg, Geoffrey, Abdennur, Nezar, Imakaev, Maxim, Goloborodko, Anton, Mirny, Leonid A.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512960/
https://ncbi.nlm.nih.gov/pubmed/29728444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/sqb.2017.82.034710
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