Dilute-and-shoot analysis of therapeutic monoclonal antibody variants in fermentation broth: a method capability study

Monoclonal antibodies (mAbs) are widely applied as highly specific and efficient therapeutic agents for various medical conditions, including cancer, inflammatory and autoimmune diseases. As protein production in cellular systems inherently generates a multitude of molecular variants, manufacturing...

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Bibliographic Details
Published in:MAbs
Main Authors: Regl, Christof, Wohlschlager, Therese, Esser-Skala, Wolfgang, Wagner, Iris, Samonig, Martin, Holzmann, Johann, Huber, Christian G.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512939/
https://ncbi.nlm.nih.gov/pubmed/30668249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2018.1563034
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