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Beyond DNA repair: the novel immunological potential of PARP inhibitors

Loss of excision repair cross-complementation group 1 (ERCC1), frequently found in lung cancer, and mutations in breast cancer type 1/2 susceptibility genes (BRCA1/2), often found in ovarian, breast and prostate cancers, confer sensitivity to poly-(ADP-ribose) polymerase inhibitors (PARPi). Our work...

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Publicat a:Mol Cell Oncol
Autors principals: Chabanon, Roman M., Soria, Jean-Charles, Lord, Christopher J., Postel-Vinay, Sophie
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512907/
https://ncbi.nlm.nih.gov/pubmed/31131303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2019.1585170
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