Spectral Imaging of FRET-Based Sensors Reveals Sustained cAMP Gradients in Three Spatial Dimensions

Cyclic AMP is a ubiquitous second messenger that orchestrates a variety of cellular functions over different timescales. The mechanisms underlying specificity within this signaling pathway are still not well understood. Several lines of evidence suggest the existence of spatial cAMP gradients within...

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Publicat a:Cytometry A
Autors principals: Annamdevula, Naga S., Sweat, Rachel, Griswold, John R., Trinh, Kenny, Hoffman, Chase, West, Savannah, Deal, Joshua, Britain, Andrea L., Jalink, Kees, Rich, Thomas C., Leavesley, Silas J.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512796/
https://ncbi.nlm.nih.gov/pubmed/30176184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.a.23572
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