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A18 STRESS TRIGGERS LOSS OF TOLERANCE TO FOOD ANTIGEN CAUSING HISTAMINE MEDIATED NEURON HYPEREXCITABILITY IN A PRECLINICAL MODEL OF IBS.

BACKGROUND: Food is a common trigger of IBS symptoms but the etiology is unclear. Increased levels of immune mediators that sensitize nerves (e.g. histamine) have been reported in IBS patients. While systemic food allergy is not a feature of IBS, it is unknown if loss of tolerance to an antigen prom...

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Dettagli Bibliografici
Pubblicato in:J Can Assoc Gastroenterol
Autori principali: Lopez Lopez, C D, Jaramillo Polanco, J O, Yu, Y, Vanner, S, Berin, C, Reed, D E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512520/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwz006.017
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