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E2F1 represses β‐catenin/TCF activity by direct up‐regulation of Siah1

Transcription factor E2F1 is a key regulator of cell proliferation and apoptosis. Its activity is strictly controlled by the pRB/E2F pathway. In the majority of cancer cells, however, this pathway is frequently found deregulated, and the underlying mechanism involving transcriptional control by E2F1...

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Foilsithe in:J Cell Mol Med
Main Authors: Xie, Wei, Jin, Lei, Mei, Yide, Wu, Mian
Formáid: Artigo
Teanga:Inglês
Foilsithe: Blackwell Publishing Ltd 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512383/
https://ncbi.nlm.nih.gov/pubmed/20187294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00423.x
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