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Osteopontin promotes gastric cancer metastasis by augmenting cell survival and invasion through Akt‐mediated HIF‐1α up‐regulation and MMP9 activation

Osteopontin (OPN) is a secreted, integrin‐binding matrix phosphorylated glycoprotein. OPN has been shown to facilitate the progression and metastasis of malignancies and has prognostic value in several types of cancer, including gastric cancer. However, the functional mechanism of OPN mediated metas...

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Bibliografske podrobnosti
izdano v:	J Cell Mol Med
Main Authors:	Song, Gang, Ouyang, Gaoliang, Mao, Yubin, Ming, Yanlin, Bao, Shideng, Hu, Tianhui
Format:	Artigo
Jezik:	Inglês
Izdano:	Blackwell Publishing Ltd 2008
Teme:	Articles
Online dostop:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6512381/ https://ncbi.nlm.nih.gov/pubmed/19602039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00540.x
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Osteopontin promotes gastric cancer metastasis by augmenting cell survival and invasion through Akt‐mediated HIF‐1α up‐regulation and MMP9 activation

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