Osteopontin promotes gastric cancer metastasis by augmenting cell survival and invasion through Akt‐mediated HIF‐1α up‐regulation and MMP9 activation

Osteopontin (OPN) is a secreted, integrin‐binding matrix phosphorylated glycoprotein. OPN has been shown to facilitate the progression and metastasis of malignancies and has prognostic value in several types of cancer, including gastric cancer. However, the functional mechanism of OPN mediated metas...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Cell Mol Med
Main Authors: Song, Gang, Ouyang, Gaoliang, Mao, Yubin, Ming, Yanlin, Bao, Shideng, Hu, Tianhui
פורמט: Artigo
שפה:Inglês
יצא לאור: Blackwell Publishing Ltd 2008
נושאים:
Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512381/
https://ncbi.nlm.nih.gov/pubmed/19602039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00540.x
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