The histone deacetylase inhibitor valproic acid alters growth properties of renal cell carcinoma in vitro and in vivo

Histone deacetylase (HDAC) inhibitors represent a promising class of antineoplastic agents which affect tumour growth, differentiation and invasion. The effects of the HDAC inhibitor valproic acid (VPA) were tested in vitro and in vivo on pre‐clinical renal cell carcinoma (RCC) models. Caki‐1, KTC‐2...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Jones, Jon, Juengel, Eva, Mickuckyte, Ausra, Hudak, Lukasz, Wedel, Steffen, Jonas, Dietger, Blaheta, Roman A.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2008
Assuntos:
Small Molecules: Molecular Bullets
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512366/
https://ncbi.nlm.nih.gov/pubmed/18657224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00436.x
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