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Analysis of Pre-existing IgG and IgM Antibodies against Polyethylene Glycol (PEG) in the General Population

Circulating antibodies (Ab) that specifically bind polyethylene glycol (PEG), a biocompatible polymer routinely used in protein and nanoparticle therapeutics, have been associated with reduced efficacy of and/or adverse reactions to therapeutics modified with or containing PEG. Unlike most antidrug...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Yang, Qi, Jacobs, Timothy M., McCallen, Justin D., Moore, Dominic T., Huckaby, Justin T., Edelstein, Jasmine N., Lai, Samuel K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512330/
https://ncbi.nlm.nih.gov/pubmed/27804292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.6b03437
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