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Association of Industry and Academic Sponsorship With Negative Phase 3 Oncology Trials and Reported Outcomes on Participant Survival: A Pooled Analysis

IMPORTANCE: Only 3.4% of cancer drugs evaluated in phase 1 trials are approved by the US Food and Drug Administration, with most failing in phase 3 trials. OBJECTIVE: To investigate whether an association exists between the sponsorship and conduct of a negative phase 3 randomized clinical trial (RCT...

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Vydáno v:JAMA Netw Open
Hlavní autoři: Addeo, Alfredo, Weiss, Glen J., Gyawali, Bishal
Médium: Artigo
Jazyk:Inglês
Vydáno: American Medical Association 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512293/
https://ncbi.nlm.nih.gov/pubmed/31074821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamanetworkopen.2019.3684
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