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A3 A PROOF-OF-CONCEPT, PHASE 2 CLINICAL TRIAL OF THE GI SAFETY OF A HYDROGEN SULFIDE-RELEASING ANTI-INFLAMMATORY DRUG (ATB-346)
BACKGROUND: Hydrogen sulfide (H(2)S) is a naturally occurring mediator produced by intestinal bacteria and various eukaryotic cells, which can exert protective and analgesic effects. ATB-346 is a H(2)S-releasing derivative of naproxen. In animals, ATB-346 produces negligible gastrointestinal (GI) da...
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| Publicado no: | J Can Assoc Gastroenterol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6512241/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwz006.002 |
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