The Dosage of the Derivative of Clostridium Ghonii (DCG) Spores Dictates Whether an IFNγ/IL-9 or a Strong IFNγ Response Is Elicited in TC-1 Tumour Bearing Mice

BACKGROUND: Anaerobic Clostridial spores (CG) cause significant oncolysis in hypoxic tumour microenvironment and result in tumour regression in both animal models and clinical trials. The immune mediated response plays a critical role in the antitumour effect by the anaerobic spore treatment. METHOD...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Ni, Guoying, Wang, Yong, Good, David, Yuan, Jianwei, Pan, Xuan, Wei, Jou, Liu, Xiaosong, Wei, Ming Q.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512072/
https://ncbi.nlm.nih.gov/pubmed/31183361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/1395138
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