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Second-Generation Tryptamine Derivatives Potently Sensitize Colistin Resistant Bacteria to Colistin

[Image: see text] Antibiotic resistance has significantly increased since the beginning of the 21st century. Currently, the polymyxin colistin is typically viewed as the antibiotic of last resort for the treatment of multidrug resistant Gram-negative bacterial infections. However, increased colistin...

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Vydáno v:ACS Med Chem Lett
Hlavní autoři: Minrovic, Bradley M., Hubble, Veronica B., Barker, William T., Jania, Leigh A., Melander, Roberta J., Koller, Beverly H., Melander, Christian
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2019
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512003/
https://ncbi.nlm.nih.gov/pubmed/31098007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00135
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