Next-level riboswitch development—implementation of Capture-SELEX facilitates identification of a new synthetic riboswitch

The development of synthetic riboswitches has always been a challenge. Although a number of interesting proof-of-concept studies have been published, almost all of these were performed with the theophylline aptamer. There is no shortage of small molecule-binding aptamers; however, only a small fract...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Boussebayle, Adrien, Torka, Daniel, Ollivaud, Sandra, Braun, Johannes, Bofill-Bosch, Cristina, Dombrowski, Max, Groher, Florian, Hamacher, Kay, Suess, Beatrix
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Synthetic Biology and Bioengineering
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511860/
https://ncbi.nlm.nih.gov/pubmed/30957848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz216
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